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60 TyurinaY

In more detail, a lower KYNA/QUIN ratio has been found typically linked to mood disorders, while lower KYNA/KYN and increased KYN/TRP ratios have been detected more specifically in both schizophrenia and major depressive disorder (5860)

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High homocysteine is associated with an increased risk of over one hundred diseases, including accelerated brain shrinkage

Acknowledgments The authors gratefully acknowledge the support of Sidra Medicine, Qatar, for providing institutional resources that facilitated this review